Adamec M, Janousek L, Lipár K, Hampl F, Saudek F, Koznarová R, Boucek P, Havrdová T
IKEM Prague, Prague, Czech Republic.
Transplant Proc. 2004 May;36(4):1093-4. doi: 10.1016/j.transproceed.2004.05.027.
Although the number of pancreas transplants has increased significantly in previous years, debate continues concerning the optimum technique for exocrine pancreas drainage. Enteric drainage (ED) has recently been increasingly popular due to the long-term complications with bladder drainage (BD). We prospectively assigned 40 consecutive pancreas transplant recipients to either bladder (n = 20) or enteric (n = 20) drainage. Patient, kidney, and pancreas graft survival rates at 1 year after simultaneous kidney-pancreas transplantation were 95%, 95%, 85%, for BD group and 90%, 85%, 85% for ED group, respectively. Surgical complications were not significantly different between the two groups. The incidence of acute rejection, major infections, and CMV disease were similar between groups. The length of the initial hospital stay was likewise comparable. However, the BD group showed a slight increase in the number of urologic complications, metabolic acidosis, and dehydration. Based on the results of our study, patient and graft survivals were excellent irrespective of technique.
尽管在过去几年中胰腺移植的数量显著增加，但关于外分泌胰腺引流的最佳技术仍存在争议。由于膀胱引流（BD）存在长期并发症，肠内引流（ED）近来越来越受欢迎。我们前瞻性地将40例连续的胰腺移植受者分为膀胱引流组（n = 20）和肠内引流组（n = 20）。在同期肾胰腺移植术后1年，BD组的患者、肾脏和胰腺移植物存活率分别为95%、95%、85%，ED组分别为90%、85%、85%。两组的手术并发症无显著差异。两组间急性排斥反应、主要感染和巨细胞病毒疾病的发生率相似。初始住院时间同样相当。然而，BD组的泌尿系统并发症、代谢性酸中毒和脱水的数量略有增加。根据我们的研究结果，无论采用何种技术，患者和移植物的存活率都很高。
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