Conway D H, Mackie C
Department of Anaesthesia, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.
Anaesthesia. 2004 Jul;59(7):652-7. doi: 10.1111/j.1365-2044.2004.03755.x.
Continuous flow positive pressure devices bridge the gap between mechanical and unsupported ventilation in patients recovering from critical illness. At this point, patients are often fully awake, yet the inflated tracheostomy cuff prevents them from speaking or swallowing. The aim of this study was to investigate the effects of cuff deflation. After ethics committee approval and informed consent, we recorded airway pressures with catheters placed 3 cm beyond the distal tracheostomy tip, respiratory rate, heart rate and peripheral oxygen saturation with continuous positive airway pressures set at 5, 7.5 and 10 cmH(2)O with the cuff inflated and deflated. Sixteen patients completed the study. There were small falls in end expiratory pressure on cuff deflation. The median (interquartile range) pressure drop with set airway pressure of 5 cmH(2)O was 0.25 (0-1.4) mmHg, which increased to 1 (0-3) mmHg at 7.5 cmH(2)O and 1.5 (0-4) mmHg at 10 cmH(2)O. These changes were not clinically significant and cardiopulmonary parameters remained stable. All patients were able to vocalise following cuff deflation. Twelve patients passed a blue dye swallow screen within a day of tolerating cuff deflation. These results suggest that pressures fall slightly following cuff deflation but this is associated with respiratory stability and may allow patients to talk and swallow.
持续气流正压装置弥合了重症康复患者机械通气与自主通气之间的差距。此时,患者通常已完全清醒,但充气的气管造口术套管会妨碍他们说话或吞咽。本研究的目的是调查套管放气的影响。经伦理委员会批准并获得知情同意后,我们使用放置在气管造口术远端尖端3厘米以外的导管记录气道压力,记录持续气道正压分别设置为5、7.5和10厘米水柱时套管充气和放气状态下的呼吸频率、心率和外周血氧饱和度。16名患者完成了研究。套管放气后呼气末压力略有下降。设定气道压力为5厘米水柱时,压力下降的中位数(四分位间距)为0.25(0 - 1.4)毫米汞柱,在7.5厘米水柱时增至1(0 - 4)毫米汞柱,在10厘米水柱时为1.5(0 - 4)毫米汞柱。这些变化在临床上并不显著,心肺参数保持稳定。所有患者在套管放气后都能够发声。12名患者在耐受套管放气一天内通过了蓝色染料吞咽筛查。这些结果表明,套管放气后压力略有下降,但这与呼吸稳定性相关,并且可能使患者能够说话和吞咽。