Dumont Francis J
Medor Consulting, 421 Dogwood Avenue, Egg Harbor Twp, NJ 08234, USA.
Curr Opin Investig Drugs. 2004 May;5(5):542-50.
ISAtx-247 is a ciclosporin A analog under development by Isotechnika and Roche as an immunosuppressant for the potential prevention of organ rejection after transplantation, and for the potential treatment of autoimmune diseases such as rheumatoid arthritis, psoriasis and type 1 diabetes. A phase II renal transplantation study had been completed by June 2003.
ISAtx - 247是Isotechnika公司和罗氏公司正在研发的一种环孢素A类似物,作为一种免疫抑制剂,用于潜在预防移植后器官排斥反应,以及潜在治疗类风湿性关节炎、银屑病和1型糖尿病等自身免疫性疾病。到2003年6月,一项II期肾移植研究已经完成。