多环芳烃负载锡试剂的设计：一类可轻松从反应混合物中除去的新型锡试剂。

Design of polyaromatic hydrocarbon-supported tin reagents: a new family of tin reagents easily removable from reaction mixtures.

作者信息

Stien Didier, Gastaldi Stéphane

机构信息

CNRS-UPS 2561, 16 avenue André Aron, 97300 Cayenne, French Guiana, France.

出版信息

J Org Chem. 2004 Jun 25;69(13):4464-70. doi: 10.1021/jo049868o.

DOI:10.1021/jo049868o

PMID:15202902

Abstract

We report in this paper the preparation and use of stannanes 11, 12a, and 12b, compounds whose 3-pyrenylpropyl side chain affinity for activated carbon simplifies tin removal and product isolation. Our pyrene-supported reagents can be used for radical reductions and cyclizations (11), radical and cationic allylations (12a), and Stille couplings (12b) in much the same way as tributyltin derivatives.

摘要

我们在本文中报告了锡烷11、12a和12b的制备及应用，这些化合物的3-芘基丙基侧链对活性炭具有亲和力，简化了锡的去除和产物的分离。我们的芘负载试剂可用于自由基还原和环化反应（11）、自由基和阳离子烯丙基化反应（12a）以及Stille偶联反应（12b），其方式与三丁基锡衍生物大致相同。