Amano T, Okita Y, Okinaga T, Matsui T, Nishiyama I, Hoshi M
Department of Life Science, Tokyo Institute of Technology, Yokohama, Japan.
Biochem Biophys Res Commun. 1992 Aug 31;187(1):274-8. doi: 10.1016/s0006-291x(05)81488-3.
In the starfish, Asterina pectinifera, egg jelly induces the degradation of sperm histones as well as the acrosome reaction. We have isolated histone degradation-inducing components from the egg jelly. The histone degradation and the acrosome reaction are induced by a co-operative action of ARIS, which is an extremely large, sulfated glycoprotein with diffusible substance(s) in the jelly. Co-ARIS I, a steroidal saponin of the jelly, is effective to induce both reactions in the presence of ARIS.