Yin Guosheng, Hu Jianhua
Department of Biostatistics, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
J Biopharm Stat. 2004 May;14(2):389-402. doi: 10.1081/BIP-120037188.
With right-censored failure time data, we propose procedures to construct simultaneous confidence bands for the survival curve of a given subject under the additive risk model. The distribution of the subject-specific cumulative hazard function can be approximated with a zero-mean Gaussian process, which can be generated through simulation methods. We propose two different simulation schemes to obtain the distribution of the supremum of the cumulative hazard process over the entire time range. The two simulation approaches are asymptotically equivalent, whereas the numerical forms are different. We construct two types of confidence bands, namely the equal precision band and the Hall-Wellner type band, through choosing suitable weight functions. Monte Carlo simulation studies show that both of the proposed confidence bands are appropriate for finite sample sizes. We illustrate the new proposal with a real example.
对于右删失失效时间数据,我们提出了在加性风险模型下为给定个体的生存曲线构建同时置信带的方法。个体特定累积风险函数的分布可以用零均值高斯过程近似,该过程可通过模拟方法生成。我们提出两种不同的模拟方案来获得累积风险过程在整个时间范围内的上确界分布。这两种模拟方法渐近等价,但数值形式不同。通过选择合适的权重函数,我们构建了两种类型的置信带,即等精度带和霍尔 - 韦尔纳型带。蒙特卡罗模拟研究表明,所提出的两种置信带对于有限样本量都是合适的。我们用一个实际例子说明了新方法。