伤寒热作为肝、脾和骨髓肉芽肿的罕见病因。

Typhoid fever as a rare cause of hepatic, splenic, and bone marrow granulomas.

作者信息

Mert Ali, Tabak Fehmi, Ozaras Resat, Ozturk Recep, Aki Hilal, Aktuglu Yildirim

机构信息

Cerrahpasa Medical Faculty, Infectious Diseases and Clinical Microbiology, University of Istanbul, 34303 Aksaray, Istanbul, Turkey.

出版信息

Intern Med. 2004 May;43(5):436-9. doi: 10.2169/internalmedicine.43.436.

DOI:10.2169/internalmedicine.43.436

PMID:15206561

Abstract

During the course of typhoid fever, the usual histologic finding of the liver is "nonspecific reactive hepatitis." Hepatic granuloma (HG) is a rare complication of typhoid fever. We present two cases of typhoid fever with HG and review the relevant literature. Case 1 (a 53-year-old female) was found to have both hepatic and splenic granulomas. This is the first case of typhoid fever with splenic granulomas in the English language literature. Case 2 (a 66-year-old male) developed granulomas in the bone marrow in addition to HG. It should be considered that typhoid fever may lead to granulomas in several organs.

摘要

在伤寒热病程中，肝脏常见的组织学表现为“非特异性反应性肝炎”。肝肉芽肿（HG）是伤寒热的一种罕见并发症。我们报告两例伴有HG的伤寒热病例并复习相关文献。病例1（一名53岁女性）被发现同时有肝脏和脾脏肉芽肿。这是英文文献中首例伴有脾脏肉芽肿的伤寒热病例。病例2（一名66岁男性）除HG外，骨髓中也出现了肉芽肿。应该认识到伤寒热可能导致多个器官出现肉芽肿。