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参照组的选择与抗生素耐药性结果

Reference group choice and antibiotic resistance outcomes.

作者信息

Kaye Keith S, Engemann John J, Mozaffari Essy, Carmeli Yehuda

机构信息

Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

Emerg Infect Dis. 2004 Jun;10(6):1125-8. doi: 10.3201/eid1006.020665.

Abstract

Two types of cohort studies examining patients infected with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) were contrasted, using different reference groups. Cases were compared to uninfected patients and patients infected with the corresponding, susceptible organism. VRE and MRSA were associated with adverse outcomes. The effect was greater when uninfected control patients were used.

摘要

对两类队列研究进行了对比,这两类研究考察了感染耐甲氧西林金黄色葡萄球菌(MRSA)和耐万古霉素肠球菌(VRE)的患者,它们使用了不同的参照组。将病例与未感染患者以及感染相应敏感微生物的患者进行了比较。VRE和MRSA与不良结局相关。当使用未感染的对照患者时,这种影响更大。

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