临床试验转诊资源。17-AG和17-DMAG的当前临床试验。 - Suppr

Clinical trials referral resource. Current clinical trials of 17-AG and 17-DMAG.

作者信息

Ivy Percy S, Schoenfeldt Mason

机构信息

National Cancer Institute, Bethesda, MD, USA.

出版信息

Oncology (Williston Park). 2004 May;18(5):610, 615, 619-20.

PMID:15209189

Abstract

摘要

相似文献

Clinical trials referral resource. Current clinical trials of 17-AG and 17-DMAG.

Oncology (Williston Park). 2004 May;18(5):610, 615, 619-20.

[Heat shock protein 90: novel target for cancer therapy].

Ai Zheng. 2004 Aug;23(8):968-74.

Cancer: the rules of attraction.

Nature. 2003 Sep 25;425(6956):357-9. doi: 10.1038/425357a.

Heat shock protein inhibitor shows antitumor activity.

J Natl Cancer Inst. 2002 Aug 21;94(16):1194-5. doi: 10.1093/jnci/94.16.1194.

Induction of the hypoxia-inducible factor system by low levels of heat shock protein 90 inhibitors.

Cancer Res. 2005 Dec 1;65(23):11094-100. doi: 10.1158/0008-5472.CAN-05-1877.

Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.

Cancer Chemother Pharmacol. 2005 Aug;56(2):126-37. doi: 10.1007/s00280-004-0947-2. Epub 2005 Apr 20.

Targeting toxic proteins for turnover.

Nat Med. 2005 Oct;11(10):1052-3. doi: 10.1038/nm1005-1052.

Auditing the pharmacological accounts for Hsp90 molecular chaperone inhibitors: unfolding the relationship between pharmacokinetics and pharmacodynamics.

Mol Cancer Ther. 2003 Feb;2(2):131-8.

Combinatorial attack on multistep oncogenesis by inhibiting the Hsp90 molecular chaperone.

Cancer Lett. 2004 Apr 8;206(2):149-57. doi: 10.1016/j.canlet.2003.08.032.

Hsp90 inhibitors in the clinic.

Handb Exp Pharmacol. 2006(172):331-58. doi: 10.1007/3-540-29717-0_14.

引用本文的文献

Regulation of Geldanamycin Biosynthesis by Cluster-Situated Transcription Factors and the Master Regulator PhoP.

Antibiotics (Basel). 2019 Jun 30;8(3):87. doi: 10.3390/antibiotics8030087.

Hsp90 and Hsp40/Erdj3 are required for the expression and anti-apoptotic function of KSHV K1.

Oncogene. 2010 Jun 17;29(24):3532-44. doi: 10.1038/onc.2010.124. Epub 2010 Apr 26.

Inhibition of neuroblastoma xenograft growth by Hsp90 inhibitors.

Anticancer Res. 2006 May-Jun;26(3A):1903-8.

Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.

Appl Environ Microbiol. 2005 Aug;71(8):4862-71. doi: 10.1128/AEM.71.8.4862-4871.2005.

ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukemia.

Blood. 2005 Oct 1;106(7):2506-12. doi: 10.1182/blood-2005-03-1099. Epub 2005 Jun 21.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Clinical trials referral resource. Current clinical trials of 17-AG and 17-DMAG.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献