Hernandez-Lattuf Pedro R., Garcia Efrain, De Lezo Jose Suarez, Murphy William R. C., Hall Robert J.
Clayton Foundation Cardiovascular Laboratory, St. Luke's Episcopal Hospital and the Texas Heart Institute, Houston, Texas.
Cardiovasc Dis. 1976;3(4):394-407.
Myocardial performance in the intact human heart can be assessed from the analysis of ejection phase indices. Accordingly, among 20 consecutive patients who were studied by means of biplane left ventricular cineangio-cardiography, 18 were selected solely on the basis of high quality angiograms. The characteristics of left ventricular contraction were expressed quantitatively by the systolic ejection fraction, the mean velocity of circumferential fiber shortening at the left ventriculalr equator, and at several chords, the mean velocity of shortening of the hemichords and the mean normalized systolic ejection rate. All 18 patients had abnormalities of contraction based on the velocity of the hemichords. Both ejection fraction and mean normalized systolic ejection rate showed a low sensitivity in detecting depressed myocardial function in patients with segmental asynergy. Equatorial V(CF) provided additional information only when the affected areas were adjacent to the left ventricular minor axis. The sensitivity of this index was markedly increased by construction of several chords perpendicular to the left ventricular long axis (segmental V(CF)). However, when only one wall was affected, measurement of the velocity of shortening of the hemichords provided a better definition of the regional performance.
完整人体心脏的心肌功能可通过射血期指标分析来评估。因此，在通过双平面左心室电影血管造影术进行研究的连续20例患者中，仅根据高质量血管造影选择了18例。左心室收缩的特征通过收缩期射血分数、左心室赤道处圆周纤维缩短的平均速度、在几根弦上、半弦缩短的平均速度以及平均标准化收缩期射血率来定量表示。基于半弦速度，所有18例患者均有收缩异常。射血分数和平均标准化收缩期射血率在检测节段性协同失调患者心肌功能降低方面均显示出低敏感性。赤道圆周纤维缩短速度（V(CF)）仅在受影响区域与左心室短轴相邻时才提供额外信息。通过构建几根垂直于左心室长轴的弦（节段性V(CF)），该指标的敏感性显著提高。然而，当仅一个壁受影响时，半弦缩短速度的测量能更好地界定局部功能。
