Hess S L, Bricker J T, Garson A, Ott D A, Reul G J, Cooley D A
The Lillie Frank Abercrombie Section of Cardiology, Texas Children's Hospital, Houston, Texas, USA.
Tex Heart Inst J. 1992;19(1):15-20.
Subaortic obstruction is a potential problem in patients with single ventricle and a subaortic outflow chamber. Previous reports have indicated an association between pulmonary artery banding and the development of subaortic obstruction. The purpose of this study was to determine the incidence of subaortic obstruction in our patients with this cardiac anomaly who have undergone pulmonary artery banding, and to determine the eventual outcome in those who did develop obstruction. By reviewing cardiac catheterizations performed between 1977 and 1985, we found 36 patients with single ventricle and a subaortic outflow chamber. Ten patients had been lost to follow-up or had died within 3 months of banding. Twelve of the remaining 26 patients developed a pressure gradient between the left ventricle and ascending aorta, although 7 of these 12 had minimal gradients. Eight of the 12 have undergone further surgery, with the best results in patients who underwent a combined modified Fontan and Damus-Kaye-Stansel procedure. We believe that although subaortic obstruction may develop in patients with single ventricle after pulmonary artery banding, the degree of obstruction is often minimal, and in more severe cases the obstruction can be alleviated with a Damus-Kaye-Stansel procedure. (Texas Heart Institute Journal 1992; 19:15-20)
主动脉瓣下狭窄是单心室合并主动脉瓣下流出腔患者的一个潜在问题。既往报道指出肺动脉环扎术与主动脉瓣下狭窄的发生有关。本研究的目的是确定在我们医院接受肺动脉环扎术的此类心脏畸形患者中主动脉瓣下狭窄的发生率,并确定那些发生狭窄患者的最终结局。通过回顾1977年至1985年间进行的心脏导管检查,我们发现36例单心室合并主动脉瓣下流出腔的患者。10例患者失访或在环扎术后3个月内死亡。其余26例患者中有12例在左心室和升主动脉之间出现了压力阶差,尽管这12例中的7例压力阶差极小。12例中的8例接受了进一步手术,接受改良Fontan和Damus-Kaye-Stansel联合手术的患者效果最佳。我们认为,尽管肺动脉环扎术后单心室患者可能会发生主动脉瓣下狭窄,但狭窄程度通常较轻,在更严重的情况下,可通过Damus-Kaye-Stansel手术缓解狭窄。(《德克萨斯心脏研究所杂志》1992年;19:15 - 20)