甲状腺原发性弥漫性大B细胞淋巴瘤化疗后18F-FDG PET出现假阳性结果：一例报告

False-positive finding on 18F-FDG PET after chemotherapy for primary diffuse large B-cell lymphoma of the thyroid: a case report.

作者信息

Marchesi Maurizio, Biffoni Marco, Biancari Fausto

机构信息

Division of General Surgery, Department of Surgical Sciences, University La Sapienza, Rome, Italy.

出版信息

Jpn J Clin Oncol. 2004 May;34(5):280-1. doi: 10.1093/jjco/hyh065.

DOI:10.1093/jjco/hyh065

PMID:15231864

Abstract

Primary non-Hodgkin lymphoma of the thyroid is an uncommon disease. It is a potentially aggressive disease and diffuse large B-cell lymphoma of the thyroid may result in 5 year survival rates <50%. Hence adequate follow-up and multimodality treatment for recurrent or persistent disease are required. Since 18F-FDG PET is considered the imaging method of choice for the detection and staging of lymphoma, this was used for restaging of a case of diffuse large B-cell lymphoma of the thyroid after chemotherapy and its diagnostic value is questioned in the present case report. In fact, PET showed a false-positive finding which led to unnecessary surgery.

摘要

原发性甲状腺非霍奇金淋巴瘤是一种罕见疾病。它是一种具有潜在侵袭性的疾病，甲状腺弥漫性大B细胞淋巴瘤可能导致5年生存率低于50%。因此，对于复发或持续性疾病需要进行充分的随访和多模式治疗。由于18F-FDG PET被认为是淋巴瘤检测和分期的首选成像方法，本文将其用于一例甲状腺弥漫性大B细胞淋巴瘤化疗后的再分期，且在本病例报告中对其诊断价值提出质疑。事实上，PET显示了一个假阳性结果，导致了不必要的手术。