Ruan Daniel T, Warren Robert S
Department of Surgery, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA.
Surg Oncol Clin N Am. 2004 Jul;13(3):505-16, ix. doi: 10.1016/j.soc.2004.04.003.
Primary and secondary hepatic malignancies are a leading cause of death. Only a minority of patients with liver cancer are candidates for curative surgical resection. Palliative treatments for unresectable hepatic malignancies should minimize tumor-related symptoms and extend overall survival. Systemic chemotherapy is only modestly effective at both ameliorating symptoms and improving survival. This review focuses on the liver-directed therapy options for patients with advanced unresectable liver malignancies.