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[低强度脉冲超声在肱骨牵张成骨中的应用。病例报告]

[Application of low intensity, pulsed ultrasound on distraction osteogenesis of the humerus. Case report].

作者信息

Dudda M, Pommer A, Muhr G, Esenwein S A

机构信息

Chirurgische Klinik mit Poliklinik, Berufsgenossenschaftliche Kliniken Bergmannsheil, Ruhr-Universität, Bochum.

出版信息

Unfallchirurg. 2005 Jan;108(1):69-74. doi: 10.1007/s00113-004-0800-4.

Abstract

Low intensity pulsed ultrasound accelerates fracture healing both clinically and experimentally. Based on recently published animal studies, an improvement in regenerative bone maturation after distraction osteogenesis due to low intensity, pulsed ultrasound is also expected. We report on an 18 year-old female patient suffering from an acquired shortening of the right upper arm of 10 cm after humeral osteitis as a baby. The patient was admitted to hospital for corticotomy and distraction osteogenesis at the afflicted humerus. Due to the published experimental results in animals which indicate an improvement in bone regeneration during callotasis with the additional application of low intensity, pulsed ultrasound, we decided to try this procedure. The calculated distraction consolidation index was 21 days/cm, which is below the mean of 30 days/cm reported in the literature for humeral lengthening by distraction osteogenesis. The calculated healing index according to Paley was 0.7 months/cm in our patient. Compared to reference data, in which a range of from 0.87 months/cm to 1.5 months/cm is reported, our patient showed an accelerated maturation of distraction callus. The duration of treatment of the patient was clearly shortened by the additional application of low intensity, pulsed ultrasound. If distraction osteogenesis is correctly indicated, the early use of low intensity, pulsed ultrasound should be considered, since an acceleration of callus formation with consecutive shortening of treatment time could be attained while wearing an external fixator, leading to a decrease in cumulative complications, such as pin tract infections. Further studies from our research group regarding this topic will follow.

摘要

低强度脉冲超声在临床和实验中均能加速骨折愈合。基于最近发表的动物研究,预计低强度脉冲超声也会使牵张成骨术后再生骨的成熟度得到改善。我们报告了一名18岁女性患者,她在婴儿期患肱骨骨炎后,右上肢后天性缩短了10厘米。该患者因患侧肱骨行皮质切开术和牵张成骨术而入院。由于已发表的动物实验结果表明,在骨痂形成期额外应用低强度脉冲超声可改善骨再生,我们决定尝试此方法。计算得出的牵张巩固指数为21天/厘米,低于文献报道的肱骨牵张成骨延长术平均30天/厘米的数值。根据佩利方法计算,我们患者的愈合指数为0.7个月/厘米。与报道的0.87个月/厘米至1.5个月/厘米的参考数据相比,我们的患者显示出牵张骨痂成熟加速。通过额外应用低强度脉冲超声,该患者的治疗时间明显缩短。如果正确选择牵张成骨术,应考虑早期使用低强度脉冲超声,因为在佩戴外固定器时可加速骨痂形成并连续缩短治疗时间,从而减少诸如针道感染等累积并发症。我们研究小组将对此主题开展进一步研究。

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