Biavatti Maique W, Koerich Cesar A, Henck Carlos H, Zucatelli Enderson, Martineli Fernanda H, Bresolin Tania B, Leite Silvana N
Universidade do Vale do Itajaí (UNIVALI), Centro de Ciências da Sadde (CCS), Curso de Farmácia, CP 360, 88303-202, Itajaí, Santa Catarina (SC), Brazil.
Z Naturforsch C J Biosci. 2004 Mar-Apr;59(3-4):197-200. doi: 10.1515/znc-2004-3-412.
The 'guaco' lianous herb Mikania laevigata, which is widespread in Southern Brazil, is traditionally used to treat bronchitis, asthma and cough. This work investigates the influence of the extraction method, solvent:drug ratio, ethanol proportion, harvest season (summer or winter) and solvent heating on the physicochemical profile of the extracts (dry weight, density, pH) and the coumarin (1,2-benzopyrone) content determined by LC. Among the results obtained, it is observed that higher ethanol content increases the amount of coumarin in the extract. Leaves harvested in summer also produce an extract with a high coumarin yield. The most efficient method of extraction is percolation, independent of the solvent used.
“瓜科”藤本植物光滑薇甘菊广泛分布于巴西南部，传统上用于治疗支气管炎、哮喘和咳嗽。本研究调查了提取方法、溶剂与药物比例、乙醇比例、收获季节（夏季或冬季）以及溶剂加热对提取物的理化性质（干重、密度、pH值）和通过液相色谱法测定的香豆素（1,2-苯并吡喃）含量的影响。在所获得的结果中，可以观察到较高的乙醇含量会增加提取物中香豆素的含量。夏季收获的叶子也能产生香豆素产量高的提取物。最有效的提取方法是渗漉法，与所使用的溶剂无关。
