Elstrom Rebecca L, Tsai Donald E, Vergilio Jo-Anne, Downs Lisa H, Alavi Abass, Schuster Stephen J
Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, 17104, USA.
Clin Lymphoma. 2004 Jun;5(1):62-4. doi: 10.3816/clm.2004.n.012.
[18F]Fluorodeoxyglucose (FDG) positron emission tomography (PET) is increasingly used for the clinical staging of lymphomas and for assessment of response to therapy. We report the case of a woman with classic Hodgkin's lymphoma who had marked FDG uptake by tumor and bone marrow suggestive of diffuse marrow involvement by lymphoma. However, iliac crest bone marrow examination showed marked myeloid hyperplasia without evidence of lymphoma involvement. We discuss the implications for interpretation of FDG-PET imaging of bone marrow in lymphomas.
[18F]氟脱氧葡萄糖(FDG)正电子发射断层扫描(PET)越来越多地用于淋巴瘤的临床分期以及评估治疗反应。我们报告了一例患有经典型霍奇金淋巴瘤的女性病例,其肿瘤和骨髓有明显的FDG摄取,提示淋巴瘤弥漫性骨髓受累。然而,髂嵴骨髓检查显示明显的髓样增生,无淋巴瘤受累证据。我们讨论了FDG-PET成像在淋巴瘤骨髓解读中的意义。