成年硬骨鱼视网膜新生视杆光感受器中视紫红质表达的时间和位置。

Timing and location of rhodopsin expression in newly born rod photoreceptors in the adult teleost retina.

作者信息

Henderson Rachel G, Fernald Russell D

机构信息

Neuroscience Program, Stanford University, Jordan Hall, Building 420, Stanford, CA 94305-2130, USA.

出版信息

Brain Res Dev Brain Res. 2004 Jul 19;151(1-2):193-7. doi: 10.1016/j.devbrainres.2004.04.001.

DOI:10.1016/j.devbrainres.2004.04.001

PMID:15246705

Abstract

Labeling of newly divided retinal cells with bromodeoxyuridine (BrdU) and a rhodopsin mRNA probe revealed that rhodopsin is first expressed by new rod photoreceptors 2 days after cell birth in an adult cichlid fish. Most new cells that expressed rhodopsin had nuclei located in the vitreal half of the outer nuclear layer (ONL), lending further support to the hypothesis that movement from scleral to vitreal ONL is associated with rod differentiation.

摘要

用溴脱氧尿苷（BrdU）和视紫红质mRNA探针标记新分裂的视网膜细胞，结果显示，在成年丽鱼科鱼中，视紫红质在细胞诞生后2天首次由新的视杆光感受器表达。大多数表达视紫红质的新细胞的细胞核位于外核层（ONL）的玻璃体一半，这进一步支持了从巩膜向玻璃体ONL移动与视杆细胞分化相关的假说。