给老年大鼠补充乙酰左旋肉碱可增加大鼠后肢骨骼肌中的线粒体转录因子A含量。

Acetyl-L-carnitine dietary supplementation to old rats increases mitochondrial transcription factor A content in rat hindlimb skeletal muscles.

作者信息

Pesce V, Fracasso F, Musicco C, Lezza A M S, Cantatore P, Gadaleta M N

机构信息

Department of Biochemistry and Molecular Biology, University of Bari, Italy.

出版信息

Ann N Y Acad Sci. 2004 Jun;1019:430-3. doi: 10.1196/annals.1297.077.

DOI:10.1196/annals.1297.077

PMID:15247059

Abstract

Acetyl-L-carnitine (ALCAR) fed to old rats has been reported to partially restore mitochondrial function and ambulatory activity. The results of the effect of ALCAR dietary supplementation to 28-month-old rats on mitochondrial transcription factor A (TFAM) content of rat hindlimb skeletal muscles are reported.

摘要

据报道，给老年大鼠喂食乙酰左旋肉碱（ALCAR）可部分恢复其线粒体功能和自主活动能力。本文报道了对28月龄大鼠进行ALCAR膳食补充后，其对大鼠后肢骨骼肌线粒体转录因子A（TFAM）含量的影响结果。