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在一项药物治疗研究中,使用每日交互式语音应答技术来测量饮酒及相关行为。

Using daily interactive voice response technology to measure drinking and related behaviors in a pharmacotherapy study.

作者信息

Kranzler Henry R, Abu-Hasaballah Khamis, Tennen Howard, Feinn Richard, Young Kevin

机构信息

Lowell P. Weicker, Jr. General Clinical Research Center, Department of Psychiatry, University of Connecticut Health Center, Farmington, Connecticut 06030-2103, USA.

出版信息

Alcohol Clin Exp Res. 2004 Jul;28(7):1060-4. doi: 10.1097/01.alc.0000130806.12066.9c.

Abstract

BACKGROUND

Interactive voice response technology (IVR) allows investigators to collect daily measures of drinking, medication adherence, mood, and other treatment-relevant variables that may change day to day during a clinical trial. Despite these advantages, no published studies have used IVR in alcohol pharmacotherapy trials.

METHODS

Subjects provided daily data via IVR during the 12-week treatment period. Seven subjects completed the trial.

RESULTS

We found a high level of participant adherence to the IVR protocol, higher levels of drinking reported by IVR than by a commonly used recall method, and distinct within-day associations between daily mood and alcohol consumption: these could not be obtained through traditional assessment methods.

CONCLUSIONS

IVR seems to be feasible for the collection of daily indicators of treatment outcomes and processes in pharmacotherapy studies among problem drinkers.

摘要

背景

交互式语音应答技术(IVR)使研究人员能够收集饮酒、药物依从性、情绪以及其他在临床试验期间可能每日变化的与治疗相关变量的日常测量数据。尽管有这些优势,但尚无已发表的研究在酒精药物治疗试验中使用IVR。

方法

在为期12周的治疗期间,受试者通过IVR提供每日数据。7名受试者完成了试验。

结果

我们发现受试者对IVR方案的依从性很高,IVR报告的饮酒水平高于常用的回忆法,并且每日情绪与酒精消费之间存在明显的日内关联:这些是通过传统评估方法无法获得的。

结论

IVR似乎对于收集问题饮酒者药物治疗研究中治疗结果和过程的每日指标是可行的。

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