Giblin Sharon, Clare Linda, Livingston Gill, Howard Rob
University College London, UK.
Int J Geriatr Psychiatry. 2004 Jul;19(7):611-23. doi: 10.1002/gps.1129.
Psychosis with first onset after the age of 60, and arising in the absence of dementia or primary affective disorder, is thought to affect 2-4% of older people, and as many as half will not respond fully to medication.
This study represents a preliminary attempt to explore a number of possible psychosocial correlates of late-onset psychosis with potential relevance for a cognitive-behavioural formulation and for the development of psychosocial interventions for this group.
The nature and extent of adverse early life experiences, presence of maladaptive cognitive schemas, and morale in relation to ageing were compared for older people with a diagnosis of late-onset psychosis (LOP; n = 14) or late-onset depression (DEP; n = 13) and healthy older volunteers (HEV; n = 18) in a cross-sectional design.
Both LOP and DEP groups reported significantly higher levels of adverse life experiences than the HEV group, with between-group differences in the types of experiences described. The LOP group scored significantly higher than the HEV group on four out of five schema domains, and significantly higher than the DEP group on two domains, other-directedness and over-vigilance/inhibition. The LOP group had significantly lower overall morale in relation to ageing than the HEV group, reflecting significantly higher levels of lonely-dissatisfaction.
Life experiences, cognitive schemas and attitudes to ageing are important psychosocial correlates of LOP. These findings contribute to an understanding of the emotional world of individuals who develop psychosis in later life and may have implications for developing more effective intervention approaches.
60岁以后首次发作且无痴呆或原发性情感障碍的精神病,被认为影响2% - 4%的老年人,多达一半的患者对药物治疗反应不完全。
本研究初步尝试探索一些可能与晚发性精神病相关的社会心理因素,这些因素可能与认知行为学解释以及针对该群体的社会心理干预措施的制定相关。
采用横断面设计,比较了诊断为晚发性精神病(LOP;n = 14)或晚发性抑郁症(DEP;n = 13)的老年人以及健康老年志愿者(HEV;n = 18)的早期不良生活经历的性质和程度、适应不良认知模式的存在情况以及与衰老相关的士气。
LOP组和DEP组报告的不良生活经历水平均显著高于HEV组,且在描述的经历类型上存在组间差异。LOP组在五个模式领域中的四个领域得分显著高于HEV组,在“他人导向”和“过度警惕/抑制”两个领域得分显著高于DEP组。LOP组与衰老相关的总体士气显著低于HEV组,反映出孤独不满程度显著更高。
生活经历、认知模式和对衰老的态度是LOP重要的社会心理相关因素。这些发现有助于理解晚年患精神病个体的情感世界,并可能对开发更有效的干预方法具有启示意义。