Spitzer Carsten, Willert Carsten, Grabe Hans-Joergen, Rizos Timolaos, Möller Bertram, Freyberger Harald J
Department of Psychiatry and Psychotherapy, Ernst-Moritz-Arndt-University, Greifswald/Stralsund, Germany.
J Neuropsychiatry Clin Neurosci. 2004 Spring;16(2):163-9. doi: 10.1176/jnp.16.2.163.
The authors investigated the hypothesis that dissociation may represent a functional dysconnectivity syndrome using a transcranial magnetic stimulation (TMS) approach. Transcranial magnetic stimulation investigations that included motor thresholds and the transcallosal conduction time (TCT) reflecting the interhemispheric transfer were performed in 74 right-handed students. All subjects completed the Dissociative Experience Scale. The high dissociators had a significantly lower left hemispheric excitability than right hemispheric excitability. They also had a significantly shorter TCT from the left to the right hemisphere than did the low dissociators. These results suggest that the neural basis of dissociation may involve a cortical asymmetry with a left hemispheric superiority or, alternatively, a lack of right hemispheric integration.
作者使用经颅磁刺激（TMS）方法研究了分离可能代表一种功能性连接障碍综合征的假说。对74名右利手学生进行了经颅磁刺激研究，包括运动阈值以及反映半球间传递的胼胝体传导时间（TCT）。所有受试者均完成了分离体验量表。高分离者左半球兴奋性显著低于右半球兴奋性。与低分离者相比，他们从左半球到右半球的TCT也显著更短。这些结果表明，分离的神经基础可能涉及以左半球优势为主的皮质不对称，或者是右半球整合缺失。
