Sol V, Branland P, Chaleix V, Granet R, Guilloton M, Lamarche F, Verneuil B, Krausz P
Université de Limoges, Laboratoire de Chimie des Substances Naturelles, 123, Avenue Albert Thomas, 87060 Limoges, France.
Bioorg Med Chem Lett. 2004 Aug 16;14(16):4207-11. doi: 10.1016/j.bmcl.2004.06.016.
Twenty four aminoporphyrin derivatives have been tested in vitro for their antibacterial photoactivity against Escherichia coli and Staphylococcus aureus. Two of these compounds, bearing polyamine units, exhibited a significant activity especially against Gram-negative bacteria (E. coli).
已对24种氨基卟啉衍生物进行了体外测试，以检测它们对大肠杆菌和金黄色葡萄球菌的抗菌光活性。其中两种带有多胺单元的化合物表现出显著活性，尤其是对革兰氏阴性菌（大肠杆菌）。
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