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[201铊心肌闪烁显像在高血压患者中的重要性]

[The importance of 201-thallium myocardial scintigraphy in the hypertensive patient].

作者信息

Jäger D, Vogel A, von Dryander S, Grosskurth D, Hinrichsen M, Lemke B, Machraoui A, Melz F, Wiebe V, Barmeyer J

机构信息

Abteilung für Kardiologie und Angiologie, Ruhr-Universität Bochum.

出版信息

Dtsch Med Wochenschr. 1992 Sep 18;117(38):1423-8. doi: 10.1055/s-2008-1062459.

Abstract

Thallium-201 exercise myocardial scintigraphy was performed in 57 patients (37 males, 20 females; mean age 55.4 [43-78] years) with angina and systemic hypertension after exclusion by coronary angiography of any coronary macroangiopathy. The exercise ECG of 32 patients could not be used in the diagnosis of ischaemia because of the presence of left ventricular hypertrophy with abnormal repolarization or left bundle branch block. Abnormal haemodynamics were demonstrated at cardiac catheterization in 23 patients (Swan-Ganz). Only 10 of the studied hypertensives with normal coronary angiograms had a myocardial scintigram within normal limits, while 12 had extensive ischaemic zones in the left ventricle. All patients with left bundle branch block had evidence of exercise-dependent apical "ischaemia". Thallium-201 myocardial scintigraphy should not be used as a screening method in hypertensives with angina, because the high proportion of "false-positive" findings, in the sense of a macroangiopathy, will nevertheless require early invasive diagnosis.

摘要

对57例(男性37例,女性20例;平均年龄55.4[43 - 78]岁)患有心绞痛和系统性高血压的患者进行了铊-201运动心肌闪烁显像检查,这些患者经冠状动脉造影排除了任何冠状动脉大血管病变。32例患者的运动心电图因存在左心室肥厚伴复极异常或左束支传导阻滞而无法用于缺血性诊断。23例患者(通过Swan - Ganz导管)在心脏导管检查中显示血流动力学异常。在研究的冠状动脉造影正常的高血压患者中,只有10例心肌闪烁显像正常,而12例左心室有广泛缺血区。所有左束支传导阻滞患者均有运动依赖性心尖部“缺血”的证据。铊-201心肌闪烁显像不应作为患有心绞痛的高血压患者的筛查方法,因为从大血管病变的角度来看,“假阳性”结果比例较高,仍需要早期进行侵入性诊断。

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