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治疗急性跟腱断裂的干预措施。

Interventions for treating acute Achilles tendon ruptures.

作者信息

Khan R J K, Fick D, Brammar T J, Crawford J, Parker M J

机构信息

Trauma and Orthopaedics, Perth Orthopaedic Institute, PO Box 1125, Nedlands, Perth, WA, Australia, 6011.

出版信息

Cochrane Database Syst Rev. 2004(3):CD003674. doi: 10.1002/14651858.CD003674.pub2.

Abstract

BACKGROUND

There is lack of consensus on the best management of the acute Achilles tendon (TA) rupture. Treatment can be broadly classified into operative (open or percutaneous) and non-operative (cast immobilisation or functional bracing). Post-operative splintage can be with a rigid cast (above or below the knee) or a more mobile functional brace.

OBJECTIVES

To identify and summarise the evidence from randomised controlled trials of the effectiveness of different interventions in the treatment of acute Achilles tendon ruptures.

SEARCH STRATEGY

We searched multiple databases including the Cochrane Musculoskeletal Injuries Group specialised register (to September 2003), reference lists of articles and contacted trialists. Keywords included Achilles Tendon, Rupture, and Tendon Injuries.

SELECTION CRITERIA

All randomised and quasi-randomised trials comparing different treatment regimens for acute Achilles tendon ruptures.

DATA COLLECTION AND ANALYSIS

Three reviewers extracted data and independently assessed trial quality by use of a ten-item scale.

MAIN RESULTS

Fourteen trials involving 891 patients were included. Several of the studies had poor methodology and inadequate reporting of outcomes. Open operative treatment compared with non-operative treatment (4 trials, 356 patients) was associated with a lower risk of rerupture (relative risk (RR) 0.27, 95% confidence interval (CI) 0.11 to 0.64), but a higher risk of other complications including infection, adhesions and disturbed skin sensibility (RR 10.60, 95%CI 4.82 to 23.28). Percutaneous repair compared with open operative repair (2 studies, 94 patients) was associated with a shorter operation duration, and lower risk of infection (RR 10.52, 95% CI 1.37 to 80.52). These figures should be interpreted with caution because of the small numbers involved. Patients splinted with a functional brace rather than a cast post-operatively (5 studies, 273 patients) tended to have a shorter in-patient stay, less time off work and a quicker return to sporting activities. There was also a lower complication rate (excluding rerupture) in the functional brace group (RR 1.88 95%CI 1.27 to 2.76). Because of the small number of patients involved no definitive conclusions could be made regarding different operative techniques (1 study, 51 patients), different non-operative treatment regimes (2 studies, 90 patients), and different forms of post-operative cast immobilisation (1 study, 40 patients).

REVIEWERS' CONCLUSIONS: Open operative treatment of acute Achilles tendon ruptures significantly reduces the risk of rerupture compared to non-operative treatment, but produces a significantly higher risk of other complications, including wound infection. The latter may be reduced by performing surgery percutaneously. Post-operative splintage in a functional brace appears to reduce hospital stay, time off work and sports, and may lower the overall complication rate.

摘要

背景

对于急性跟腱断裂的最佳治疗方法,目前尚无共识。治疗方法大致可分为手术治疗(开放手术或经皮手术)和非手术治疗(石膏固定或功能性支具固定)。术后固定可采用硬性石膏(膝上或膝下)或更具灵活性的功能性支具。

目的

识别并总结不同干预措施治疗急性跟腱断裂有效性的随机对照试验证据。

检索策略

我们检索了多个数据库,包括Cochrane肌肉骨骼损伤组专业注册库(截至2003年9月)、文章参考文献列表,并联系了试验研究者。关键词包括跟腱、断裂和肌腱损伤。

入选标准

所有比较急性跟腱断裂不同治疗方案的随机和半随机试验。

数据收集与分析

三位评价者提取数据,并使用十项量表独立评估试验质量。

主要结果

纳入了14项涉及891例患者的试验。其中几项研究方法欠佳,结果报告不充分。开放手术治疗与非手术治疗相比(4项试验,356例患者),再断裂风险较低(相对风险(RR)0.27,95%置信区间(CI)0.11至0.64),但包括感染、粘连和皮肤感觉障碍在内的其他并发症风险较高(RR 10.60,95%CI 4.82至23.28)。经皮修复与开放手术修复相比(2项研究,94例患者),手术时间较短,感染风险较低(RR 10.52,95%CI 1.37至80.52)。由于涉及的病例数较少,这些数据应谨慎解读。术后使用功能性支具而非石膏固定的患者(5项研究,273例患者)住院时间往往较短,误工时间较少,恢复体育活动较快。功能性支具组的并发症发生率(不包括再断裂)也较低(RR 1.88,95%CI 1.27至2.76)。由于涉及患者数量较少,关于不同手术技术(1项研究,51例患者)、不同非手术治疗方案(2项研究,90例患者)和不同形式的术后石膏固定(1项研究,40例患者),无法得出明确结论。

评价者结论

与非手术治疗相比,急性跟腱断裂的开放手术治疗显著降低了再断裂风险,但其他并发症的风险显著更高,包括伤口感染。经皮手术可能会降低后者的风险。术后使用功能性支具固定似乎可缩短住院时间、减少误工和运动时间,并可能降低总体并发症发生率。

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