哌甲酯对与注意力缺陷/多动障碍共病的对立违抗性障碍的影响。
The effect of methylphenidate on oppositional defiant disorder comorbid with attention deficit/hyperactivity disorder.
作者信息
Serra-Pinheiro Maria Antonia, Mattos Paulo, Souza Isabella, Pastura Giuseppe, Gomes Fernanda
机构信息
Grupo de Estudos do Deficit de Atenção, Federal University of Rio de Janeiro.
出版信息
Arq Neuropsiquiatr. 2004 Jun;62(2B):399-402. doi: 10.1590/s0004-282x2004000300005. Epub 2004 Jul 20.
OBJECTIVE
To assess the effect of methylphenidate on the diagnosis of oppositional-defiant disorder (ODD) comorbid with attention-deficit hyperactivity disorder (ADHD).
METHOD
We conducted an open-label study in which 10 children and adolescents with a dual diagnosis of ODD and ADHD were assessed for their ODD symptoms and treated with methylphenidate. At least one month after ADHD symptoms were under control, ODD symptoms were reevaluated with the Parent form of the Children Interview for Psychiatric Syndromes (P-ChIPS).
RESULTS
Nine of the 10 patients no longer fulfilled diagnostic criteria for ODD after they were treated with methylphenidate for ADHD.
CONCLUSION
Methylphenidate seems to be an effective treatment for ODD, as well as for ADHD itself. The implications for the treatment of patients with ODD not comorbid with ADHD needs further investigation.
目的
评估哌甲酯对与注意力缺陷多动障碍（ADHD）共病的对立违抗障碍（ODD）诊断的影响。
方法
我们进行了一项开放标签研究，对10名患有ODD和ADHD双重诊断的儿童和青少年进行ODD症状评估，并给予哌甲酯治疗。在ADHD症状得到控制至少1个月后，使用儿童精神综合征访谈家长版（P-ChIPS）重新评估ODD症状。
结果
10名患者中有9名在接受哌甲酯治疗ADHD后不再符合ODD的诊断标准。
结论
哌甲酯似乎是治疗ODD以及ADHD本身的有效方法。对于不与ADHD共病的ODD患者治疗的影响需要进一步研究。
Zotero 插件