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氩激光和脉冲染料激光治疗后的面部葡萄酒色斑中发生多灶性基底细胞癌:既往放疗的可能作用

Multifocal basal cell carcinoma developing in a facial port wine stain treated with argon and pulsed dye laser: a possible role for previous radiotherapy.

作者信息

Jasim Zaid F, Woo Wai K, Walsh Maureen Y, Handley Julian M

机构信息

Department of Dermatology, Ulster Hospital, Belfast, UK.

出版信息

Dermatol Surg. 2004 Aug;30(8):1155-7. doi: 10.1111/j.1524-4725.2004.30345.x.

Abstract

BACKGROUND

Basal cell carcinoma occurring in port wine stain is extremely rare but has been reported after radiotherapy for port wine stain.

OBJECTIVE

The objective was to present 55-year-old man with a facial port wine stain who had multiple treatment sessions with both the argon laser and the pulsed dye laser and subsequently developed a recurrent multifocal basal cell carcinoma and highlight the treatment carried out and its effects on the outcome.

METHODS

We describe the history of the patient's port wine stain treatment, the development of skin cancer within it, and the different modalities of therapy carried out.

RESULTS

The patient developed basal cell carcinoma in his port wine stain. The possibility of a causal link between laser treatment and this skin cancer was considered but it was discovered that he had had radiotherapy treatment of his birthmark at age 9. The basal cell carcinoma was successfully treated.

CONCLUSION

This case of a clinically indistinct multifocal basal cell carcinoma arising within facial port wine stain was most likely due to previous radiotherapy treatment as a child, rather than laser treatment. Careful treatment history should identify such patients who should be followed-up for development of skin cancer.

摘要

背景

发生于葡萄酒色斑的基底细胞癌极为罕见,但已有在葡萄酒色斑放疗后发生该病的报道。

目的

本文旨在介绍一名55岁面部患有葡萄酒色斑的男性患者,其先后接受了多次氩激光和脉冲染料激光治疗,随后发生了复发性多灶性基底细胞癌,并着重阐述所采取的治疗方法及其对治疗结果的影响。

方法

我们描述了该患者葡萄酒色斑的治疗史、其中皮肤癌的发生情况以及所采用的不同治疗方式。

结果

该患者在其葡萄酒色斑内发生了基底细胞癌。考虑到激光治疗与这种皮肤癌之间可能存在因果关系,但发现他在9岁时曾对其胎记进行过放射治疗。基底细胞癌得到了成功治疗。

结论

该例发生于面部葡萄酒色斑内的临床症状不明显的多灶性基底细胞癌很可能是由于儿童时期接受过放射治疗,而非激光治疗。详细的治疗史应能识别出这类患者,应对其进行皮肤癌发生情况的随访。

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