Reynolds Maureen D, Tarter Ralph E, Kirisci Levent
Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA.
Drug Alcohol Depend. 2004 Sep 6;75(3):241-51. doi: 10.1016/j.drugalcdep.2004.03.009.
Men qualifying for substance use disorder (SUD) consequent to consumption of an illicit drug were compared according to recruitment method. It was hypothesized that volunteers would be more self-disclosing and exhibit more severe disturbances compared to randomly recruited subjects.
Personal, demographic, family, social, substance use, psychiatric, and SUD characteristics of volunteers (N = 146) were compared to randomly recruited (N = 102) subjects.
Volunteers had lower socioceconomic status, were more likely to be African American, and had lower IQ than randomly recruited subjects. Volunteers also evidenced greater social and family maladjustment and more frequently had received treatment for substance abuse. In addition, lower social desirability response bias was observed in the volunteers. SUD was not more severe in the volunteers; however, they reported a higher lifetime rate of opiate, diet, depressant, and analgesic drug use.
Volunteers and randomly recruited subjects qualifying for SUD consequent to illicit drug use are similar in SUD severity but differ in terms of severity of psychosocial disturbance and history of drug involvement. The factors discriminating volunteers and randomly recruited subjects are well known to impact on outcome, hence they need to be considered in research design, especially when selecting a sampling strategy in treatment research.
根据招募方法对因使用非法药物而符合物质使用障碍(SUD)标准的男性进行比较。假设与随机招募的受试者相比,志愿者会更愿意自我披露且表现出更严重的紊乱情况。
将志愿者(N = 146)与随机招募的受试者(N = 102)在个人、人口统计学、家庭、社会、物质使用、精神病学和SUD特征方面进行比较。
志愿者的社会经济地位较低,更有可能是非裔美国人,且智商低于随机招募的受试者。志愿者还表现出更大的社会和家庭适应不良,并且更频繁地接受过药物滥用治疗。此外,在志愿者中观察到较低的社会期望反应偏差。志愿者的SUD并不更严重;然而,他们报告的阿片类药物、节食药物、镇静剂和镇痛药的终生使用率更高。
因非法药物使用而符合SUD标准的志愿者和随机招募的受试者在SUD严重程度上相似,但在心理社会紊乱的严重程度和药物使用史方面存在差异。区分志愿者和随机招募受试者的因素众所周知会影响结果,因此在研究设计中需要考虑这些因素,尤其是在治疗研究中选择抽样策略时。