Wildemeersch D, Rowe P J
Contrel Research, Ghent, Belgium.
Contraception. 2004 Aug;70(2):169-72. doi: 10.1016/j.contraception.2004.02.006.
This study was conducted to evaluate the effect of a miniaturized frameless copper IUD (GyneFix 200 small) and a copper-levonorgestrel (GynePlant) intrauterine system (IUS) on the amount of menstrual blood loss (MBL).
In 60 Belgian women using GyneFix 200 and 21 using GynePlant, MBL was assessed with the visual assessment technique.
MBL scores in GyneFix 200 users did not change from baseline during the mean observation period of 31 months. In GynePlant users, mean MBL scores decreased by at least 50% in all but one user.
The impact of copper IUDs on MBL can be minimized by reducing the surface area of the foreign body. Reduction of MBL, without causing amenorrhea, can be obtained by adding levonorgestrel.
本研究旨在评估小型无框架铜宫内节育器(吉妮柔适200小型)和含铜左炔诺孕酮宫内节育系统(吉妮致美)对月经量(MBL)的影响。
对60名使用吉妮柔适200的比利时女性和21名使用吉妮致美的女性,采用视觉评估技术评估月经量。
在平均31个月的观察期内,使用吉妮柔适200的女性月经量评分与基线相比无变化。在使用吉妮致美的女性中,除一名使用者外,其他使用者的平均月经量评分至少降低了50%。
通过减少异物表面积可将铜宫内节育器对月经量的影响降至最低。添加左炔诺孕酮可减少月经量且不导致闭经。