Hoving Jan L, de Vet Henrica C W, Twisk Jos W R, Devillé Walter L J M, van der Windt Daniëlle, Koes Bart W, Bouter Lex M
Institute for Research in Extramural Medicine, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands Unit of Occupational and Environmental Health, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia Department of Clinical Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands Institute for NIVEL, Utrecht, The Netherlands Department of General Practice, VU University Medical Center, Amsterdam, The Netherlands Institute of General Practice, Erasmus Medical Center, Rotterdam, The Netherlands.
Pain. 2004 Aug;110(3):639-645. doi: 10.1016/j.pain.2004.05.002.
Prognostic studies on neck pain are scarce and are typically restricted to short-term follow-up only. In this prospective cohort study, indicators of short- and long-term outcomes of neck pain were identified that can easily be measured in general practice. Patients between 18 and 70 years of age, suffering for at least 2 weeks from neck pain were recruited by 42 general practitioners (GPs). Perceived recovery, pain intensity and neck dysfunction after 7 and 52 weeks were considered as outcome measures. Indicators of prognosis were identified by means of logistic regression analyses (perceived recovery) and linear regression analyses (pain intensity and neck dysfunction). In total, 183 patients were included. After 1 year, 63% had recovered. The prognostic models showed differences between short- and long-term indicators. At the short term, besides the baseline values of the respective outcome measurements, only older age (> or =40) and concomitant low back pain and headache were associated with poor outcome. At the long term, in addition to age and concomitant low back pain, previous trauma, a long duration of neck pain, stable neck pain during the 2 weeks prior to baseline measurement, and previous neck pain predicted poor prognosis. The predictive power of the models was weak: the explained variance (R(2)) varied from 24 to 36%. Patient history and physical examination give GPs little handholds to predict the prognosis for patients with sub-acute and chronic neck pain. A few indicators of a less favourable prognosis of neck pain were identified, of which older age and concomitant low back pain was the most consistent.
关于颈部疼痛的预后研究很少,且通常仅局限于短期随访。在这项前瞻性队列研究中,确定了颈部疼痛短期和长期预后的指标,这些指标在全科医疗中易于测量。42名全科医生招募了年龄在18至70岁之间、颈部疼痛至少持续2周的患者。将7周和52周后的感知恢复情况、疼痛强度和颈部功能障碍视为结局指标。通过逻辑回归分析(感知恢复)和线性回归分析(疼痛强度和颈部功能障碍)确定预后指标。总共纳入了183名患者。1年后,63%的患者康复。预后模型显示短期和长期指标存在差异。短期内,除了各自结局测量的基线值外,只有年龄较大(≥40岁)以及伴有下背部疼痛和头痛与不良结局相关。长期来看,除了年龄和伴有下背部疼痛外,既往创伤、颈部疼痛持续时间长、基线测量前2周内颈部疼痛稳定以及既往颈部疼痛预示着预后不良。模型的预测能力较弱:解释方差(R²)在24%至36%之间变化。患者病史和体格检查为全科医生预测亚急性和慢性颈部疼痛患者的预后提供的依据很少。确定了一些颈部疼痛预后较差的指标,其中年龄较大和伴有下背部疼痛最为一致。