Safriel Yair, Sclafani Salvatore, Gale Brian, Patel Divyang, Gordon David
Department of Radiology, State University of New York at Brooklyn (Downstate), New York, USA.
Emerg Radiol. 2002 Mar;9(1):55-9. doi: 10.1007/s10140-001-0192-5. Epub 2002 Feb 20.
CT pulmonary angiography is now often the first-line investigation for pulmonary emboli. When these studies are performed after hours in teaching hospitals, they are often initially interpreted by trainees. It is of great significance whether the interpretations of trainees and certified radiologists with regard to the presence of pulmonary emboli on CT pulmonary angiograms correspond, because of the morbidity and mortality of both the condition and its treatment.
Twenty-five consecutive CT pulmonary angiograms (CTPAs) of hospitalized patients were viewed at lung and soft tissue windows both on a workstation and on hard copies, at the observers' discretion. Each CTPA was divided into 28 arterial zones based on pulmonary anatomy (including the subsegmental arteries), giving a total of 700 arterial zones, and analyzed retrospectively and independently by two cross-sectional imaging specialists and four residents. Each arterial segment was rated with regard to pulmonary embolus as either high, intermediate, or low probability or not visualized. The kappa (Kappa) test, which tests for interobserver agreement, was used for statistical analysis.
At the time of the scan all patients were hospitalized for underlying conditions. Of the 25 patients studied, 9 were referred from the ICU, 7 experienced severe acute shortness of breath and respiratory failure, 5 were post-partum women, 2 had had a recent stroke, 1 patient had antithrombin III deficiency, and 1 had a diagnosis of breast cancer. The incidence of pulmonary emboli was 44%. For the main pulmonary arteries interobserver agreement was good (Kappa=0.61) and for the segmental pulmonary arteries it was fair (Kappa=0.26). For the subsegmental arteries interobserver agreement was poor (Kappa=0.16). The zones where interobserver agreement was greatest (Kappa>0.4) were the left main, left lower lobe, and the right main pulmonary arteries. Interobserver agreement was poorest (Kappa<0.05) in the left interlobar, left lower lobe lateral basal segment, right lower lobe superior segment, and left lower lobe superior segment branches. None of the patients expired due to pulmonary emboli.
Most life-threatening pulmonary emboli requiring urgent treatment are the more central emboli. This study demonstrates that trainees and certified radiologists can make similar conclusions regarding these central pulmonary emboli in hospitalized patients and that preliminary interpretations by trainees should not therefore adversely affect patient care.
CT肺动脉造影目前常作为肺栓塞的一线检查方法。在教学医院非工作时间进行这些检查时,通常由实习医生先进行初步解读。鉴于肺栓塞及其治疗的发病率和死亡率,实习医生与有资质的放射科医生对CT肺动脉造影上肺栓塞的解读是否一致具有重要意义。
由观察者自行决定,在工作站和硬拷贝上分别以肺窗和软组织窗观察25例住院患者连续的CT肺动脉造影(CTPA)。根据肺解剖结构(包括亚段动脉)将每个CTPA分为28个动脉区域,共700个动脉区域,由两名横断面影像专家和四名住院医生进行回顾性独立分析。每个动脉节段根据肺栓塞情况分为高、中、低概率或未见显影。采用检验观察者间一致性的kappa(Kappa)检验进行统计分析。
扫描时所有患者均因基础疾病住院。在研究的25例患者中,9例来自重症监护病房,7例出现严重急性呼吸急促和呼吸衰竭,5例为产后女性,2例近期有中风病史,1例患者抗凝血酶III缺乏,1例诊断为乳腺癌。肺栓塞的发生率为44%。对于主肺动脉,观察者间一致性良好(Kappa = 0.61),对于段肺动脉,一致性一般(Kappa = 0.26)。对于亚段动脉,观察者间一致性较差(Kappa = 0.16)。观察者间一致性最高(Kappa>0.4)的区域是左主肺动脉、左下叶和右主肺动脉。观察者间一致性最差(Kappa<0.05)的区域是左叶间、左下叶外侧基底段、右下叶上段和左下叶上段分支。所有患者均未因肺栓塞死亡。
大多数需要紧急治疗的危及生命的肺栓塞是更靠近中心的栓塞。本研究表明,实习医生和有资质的放射科医生对于住院患者这些中心型肺栓塞可得出相似结论,因此实习医生的初步解读不应给患者治疗带来不利影响。