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经较短去管化回肠段构建的回肠原位新膀胱(改良豪特曼法):经验与结果

Ileal orthotopic neobladder (modified Hautmann) via a shorter detubularized ileal segment: experience and results.

作者信息

Sevin Güven, Soyupek Sedat, Armağan Abdullah, Hoşcan Mustafa B, Oksay Taylan

机构信息

Department of Urology, Süleyman Demirel University, School of Medicine, 32050 Isparta, Turkey.

出版信息

BJU Int. 2004 Aug;94(3):355-9. doi: 10.1111/j.1464-410X.2004.04933.x.

Abstract

OBJECTIVE

To evaluate the clinical, urodynamic, functional, radiological and metabolic results of the ileal (modified Hautmann) orthotopic neobladder over 10 years of experience.

PATIENTS AND METHODS

Between January 1992 and March 2002, 124 men (mean age 62.4 years, range 44-76) with advanced bladder cancer had a radical cystoprostatectomy and urinary diversion via an ileal orthotopic neobladder (modified Hautmann). Only 40 cm of small bowel (detubularized ileum) was used to construct the reservoir, as a modification of the method described by Hautmann. All patients were followed periodically and their data recorded.

RESULTS

While no patients died during surgery six died (mortality rate was 5%) in the first 30 days afterward (two of them from causes unrelated to the urinary diversion surgery). The early reoperation rate was 14%; there were early complications not requiring surgery in 40 (34%) and later reoperation rate was required in 20.6%. The mean (range) maximum neobladder capacity was 550 (310-720) mL, the maximum intravesical pressure at maximum capacity 26.4 (11-48) cmH(2)O, and the minimum and maximum flow rates 25.2 (16-64) and 17.5 (11-30) mL/s, respectively. Day- and night-time continence rates were 92% and 90% after 4 years. While there was no electrolyte imbalance, there was mild to moderate metabolic acidosis in 58% of patients. There was no urethral tumour recurrence in any patient.

CONCLUSION

Detubularization of ileum to form a neobladder gives a more favourable low-pressure and high-capacity reservoir. Therefore, a shorter ileal segment can be used for orthotopic urinary diversion, to avoid various metabolic dysfunctions when using detubularized bowel, but the surgery is not as free of complications as the original technique.

摘要

目的

评估在超过10年经验中回肠(改良豪特曼法)原位新膀胱的临床、尿动力学、功能、影像学及代谢结果。

患者与方法

1992年1月至2002年3月期间,124例(平均年龄62.4岁,范围44 - 76岁)晚期膀胱癌男性患者接受了根治性膀胱前列腺切除术,并通过回肠原位新膀胱(改良豪特曼法)进行尿流改道。作为对豪特曼所描述方法的改良,仅使用40厘米小肠(去管化回肠)构建储尿囊。所有患者均接受定期随访并记录其数据。

结果

手术期间无患者死亡,但术后前30天有6例死亡(死亡率为5%)(其中2例死亡原因与尿流改道手术无关)。早期再次手术率为14%;40例(34%)出现无需手术的早期并发症,20.6%需要后期再次手术。新膀胱平均(范围)最大容量为550(310 - 720)毫升,最大容量时膀胱内最大压力为26.4(11 - 48)厘米水柱,最小和最大尿流率分别为25.2(16 - 64)和17.5(11 - 30)毫升/秒。4年后白天和夜间控尿率分别为92%和90%。虽然没有电解质失衡,但58%的患者存在轻度至中度代谢性酸中毒。所有患者均未出现尿道肿瘤复发。

结论

回肠去管化形成新膀胱可形成更有利的低压大容量储尿囊。因此,较短的回肠段可用于原位尿流改道,以避免使用去管化肠段时出现各种代谢功能障碍,但该手术不像原技术那样无并发症。

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