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19个发展中国家避孕失败的生殖后果

Reproductive consequences of contraceptive failure in 19 developing countries.

作者信息

Cleland John, Ali Mohamed M

机构信息

Centre for Population Studies, London School of Hygiene and Tropical Medicine, United Kingdom.

出版信息

Obstet Gynecol. 2004 Aug;104(2):314-20. doi: 10.1097/01.AOG.0000134789.73663.fd.

Abstract

OBJECTIVE

To ascertain the contribution of contraceptive failure to unintended births and fetal loss in developing countries.

METHODS

Nationally representative survey data from married women in 19 developing countries were analyzed. All surveys contained retrospective monthly calendars of contraceptive use and pregnancies for a 5-year period preceding each survey. Information on the intendedness of live births, ascertained earlier in the interview, were linked to the calendar data. Single-decrement life table analysis was applied to episodes of use to estimate failure probabilities. The reproductive consequences of failure were established by simple tabulation. Logistic regression was used to explore the determinants of fetal loss.

RESULTS

Reported contraceptive failure rates were similar to those derived from studies conducted mainly in the United States. About three fourths of pregnancies resulting from contraceptive failure were carried to term, and all but 16% of those were classified by the mother as unwanted or mistimed. Just over one tenth ended in fetal loss, either induced or spontaneous. Analysis of determinants of fetal loss suggested that a large proportion were induced. The median contribution of failure to all unintended births for all 19 surveys was about 15%, and the contribution to fetal loss was 12%.

CONCLUSION

The contribution of contraceptive failure in developing countries is much lower than the estimate of 50% in the United States. Despite the substantial increases in contraceptive practice that have occurred in Asia, Latin America, the Middle East, and to a lesser extent, Africa, the level of use is still below the 75% mark achieved in most industrialized countries. Nonuse of contraception remains the dominant direct cause of unintended births, and family planning promotion should remain a public health priority.

摘要

目的

确定避孕失败对发展中国家意外怀孕和胎儿流失的影响。

方法

分析了来自19个发展中国家已婚妇女的具有全国代表性的调查数据。所有调查都包含了每次调查前5年的避孕使用情况和怀孕情况的回顾性月度日历。在访谈中早些时候确定的活产意愿信息与日历数据相关联。单减寿命表分析应用于使用情况的各个阶段,以估计失败概率。通过简单列表确定失败的生殖后果。使用逻辑回归来探索胎儿流失的决定因素。

结果

报告的避孕失败率与主要在美国进行的研究得出的失败率相似。因避孕失败导致的怀孕中,约四分之三的胎儿足月出生,其中除16%外,所有这些都被母亲归类为意外或时机不当。略超过十分之一以人工流产或自然流产告终。对胎儿流失决定因素的分析表明,很大一部分是人工流产。在所有19项调查中,避孕失败对所有意外出生的平均贡献率约为15%,对胎儿流失的贡献率为12%。

结论

发展中国家避孕失败的贡献率远低于美国估计的50%。尽管亚洲、拉丁美洲、中东以及在较小程度上非洲的避孕措施使用量大幅增加,但使用水平仍低于大多数工业化国家达到的75%的水平。不使用避孕措施仍然是意外怀孕的主要直接原因,计划生育推广仍应是公共卫生的优先事项。

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