Choo Suk Jung, Park Nam Hee, Lee Sang Kwon, Kim Jong Woo, Song Jae Kwan, Song Hyun, Song Meong Gun, Lee Jae Won
Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-dong Songpa-gu, Seoul 138-736, South Korea.
Eur J Cardiothorac Surg. 2004 Aug;26(2):336-41. doi: 10.1016/j.ejcts.2004.04.003.
The incidence of sinus conversion in the enlarged left atrium after atrial fibrillation surgery is reported to be low. The purpose of the current study was to investigate the effects of atrial fibrillation surgery on mitral valve disease associated with a giant left atrium (GLA).
From July of 1997 to February of 2002, 188 patients received mitral valve and atrial fibrillation surgery. The patients were placed in either GLA group (n = 94), or NGLA group (n = 94), based on LA size. The presence and onset of sinus rhythm and the incidence and velocity of transmitral A waves were monitored during the early postoperative period and throughout the follow up period of 42 months.
The onset of postoperative sinus rhythm was slightly earlier in the NGLA group than in the GLA group at 1.3+/-0.4 days versus 3.1+/-1.2 days, respectively, (P = 0.008). The sinus conversion rates in the GLA and the NGLA groups were 91.5 and 97.9% in the early postoperative period, and 94.7 and 95.7% at 6 months after surgery, respectively. A wave appearance rates in the early postoperative period in the GLA and the NGLA groups were 62.2 and 71.7%, and continued to improve over time to 94 and 95% by 36 months, respectively. Peak A wave velocities in the early postoperative period in GLA and NGLA groups were 67.4+/-34.0 and 61.1+/-29.5 cm/s without significant change during the follow up.
The results suggest that atrial fibrillation surgery is effective at inducing sinus rhythm and restoring left atrial contractile function after concomitant mitral valve surgery regardless of LA size.
据报道,房颤手术后扩大的左心房中窦性心律转复的发生率较低。本研究的目的是探讨房颤手术对与巨大左心房(GLA)相关的二尖瓣疾病的影响。
1997年7月至2002年2月,188例患者接受了二尖瓣和房颤手术。根据左心房大小,将患者分为GLA组(n = 94)或非GLA组(n = 94)。在术后早期以及整个42个月的随访期内,监测窦性心律的存在和发作情况以及二尖瓣A波的发生率和速度。
非GLA组术后窦性心律的发作略早于GLA组,分别为1.3±0.4天和3.1±1.2天,(P = 0.008)。GLA组和非GLA组术后早期的窦性心律转复率分别为91.5%和97.9%,术后6个月分别为94.7%和95.7%。GLA组和非GLA组术后早期的A波出现率分别为62.2%和71.7%,并随时间持续改善,到36个月时分别提高到94%和95%。GLA组和非GLA组术后早期的A波峰值速度分别为67.4±34.0和61.1±29.5 cm/s,随访期间无显著变化。
结果表明,无论左心房大小如何,房颤手术在二尖瓣手术同时诱导窦性心律和恢复左心房收缩功能方面是有效的。