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手足部软骨母细胞瘤

Chondroblastoma of the hands and feet.

作者信息

Davila Jesse A, Amrami Kimberly K, Sundaram Murali, Adkins Mark C, Unni Krishnan K

机构信息

Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

出版信息

Skeletal Radiol. 2004 Oct;33(10):582-7. doi: 10.1007/s00256-004-0762-1. Epub 2004 Aug 14.

Abstract

OBJECTIVE

To review the imaging findings, age and gender distribution of chondroblastoma of the hands and feet.

DESIGN AND PATIENTS

Twenty-five cases of pathologically proven chondroblastoma of the hands and feet were reviewed. Available imaging modalities included radiographs (n=24), CT (n=3), MRI (n=5), and radionuclide bone scintigraphy (n=1). The following imaging features for each case were tabulated: location, presence of sclerotic margin, calcification, expansion, presence of fluid/fluid levels on cross-sectional imaging and surrounding edema on MRI. The images were evaluated for skeletal maturity using closure of the physeal plate in the region as a standard.

RESULTS

The average age at time of diagnosis was 23 years (range 7-57 years). Eighty-four percent (n=21) of the patients were skeletally mature. Males (20 of 25) outnumbered females by a ratio of 5:1. The bones of the foot accounted for 22 cases: calcaneus (n=8), talus (n=8), metatarsals (n=3), and the cuboid (n=3). The bones of the hand accounted for three cases: phalanx (n=1), triquetrum (n=1), and a metacarpal (n=1). Radiographically all lesions were osteolytic with identifiable calcification in 54% (13 of 24). Fluid/fluid levels were seen in four of five cases on MRI. Edema on MR images was seen in 40% (2 of 5). The size of the lesions ranged from 2 to 41 cm(2).

CONCLUSION

Chondroblastomas of the hands and feet share many of the radiographic characteristics seen in the long bones, but manifest in skeletally mature patients with a higher male to female ratio than in long bone chondroblastoma. Talar and calcaneal lesions were encountered only in males. Chondroblastoma of the wrist and hand appears to be exceptionally rare.

摘要

目的

回顾手足软骨母细胞瘤的影像学表现、年龄及性别分布。

设计与患者

回顾25例经病理证实的手足软骨母细胞瘤病例。可用的影像学检查方法包括X线片(n = 24)、CT(n = 3)、MRI(n = 5)和放射性核素骨显像(n = 1)。将每例病例的以下影像学特征制成表格:位置、硬化边缘的存在情况、钙化、膨胀、横断面成像上的液/液平面以及MRI上的周围水肿。以该区域骨骺板闭合作为标准评估图像的骨骼成熟度。

结果

诊断时的平均年龄为23岁(范围7 - 57岁)。84%(n = 21)的患者骨骼成熟。男性(25例中的20例)与女性的比例为5:1,男性多于女性。足部骨骼占22例:跟骨(n = 8)、距骨(n = 8)、跖骨(n = 3)和骰骨(n = 3)。手部骨骼占3例:指骨(n = 1)、三角骨(n = 1)和掌骨(n = 1)。X线片上所有病变均为溶骨性,54%(24例中的13例)可见钙化。MRI上5例中有4例可见液/液平面。MR图像上40%(5例中的2例)可见水肿。病变大小范围为2至41 cm²。

结论

手足软骨母细胞瘤具有许多长骨中可见的影像学特征,但多见于骨骼成熟的患者,男女比例高于长骨软骨母细胞瘤。距骨和跟骨病变仅见于男性。手腕和手部的软骨母细胞瘤似乎极为罕见。

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