Montastruc P, Mauco G
C R Seances Soc Biol Fil. 1978;172(3):560-4.
The diuretic effect of dopamine is unchanged in the dog with diabetes insipidus but the natriuretic effect of dopamine is shorter. With the normal dog propanolol delays the dopamine-induced diuresis and natriuresis but the magnitude of this double effect is unchanged. In the dog with diabetes insipidus, propanolol suppresses the dopaminergic diuresis and reduces the natriuresis.
多巴胺对尿崩症犬的利尿作用未变,但多巴胺的利钠作用持续时间较短。对于正常犬,普萘洛尔会延迟多巴胺诱导的利尿和利钠作用,但这种双重作用的程度不变。在尿崩症犬中,普萘洛尔会抑制多巴胺能利尿并减少利钠作用。