Reyes M, Pan P H
Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Int J Obstet Anesth. 2004 Apr;13(2):99-102. doi: 10.1016/j.ijoa.2003.09.004.
To our knowledge, based on a literature search, this is the first case report of successful cesarean section requiring a very low total dose of 5 mg hyperbaric spinal bupivacaine without any spinal or intravenous supplements in a morbidly obese (BMI=66 kg/m(2)) preeclamptic parturient. This parturient appeared to be more sensitive than the average to spinal anesthesia for cesarean section. Titrating the neuraxial drugs to effect with a combined spinal-epidural or epidural technique instead of a single-shot spinal may be useful in cases such as this. This report does not suggest the routine use of low-dose spinal anesthesia without supplements, but illustrates the wide variability in dosage and sensitivity to spinal anesthetics, and suggests that further research is needed in this area, particularly in morbidly obese parturients. Furthermore, it emphasizes the importance of vigilance and frequent blood pressure and respiration monitoring even in cases of low-dose spinal analgesia, such as that used in the combined spinal-epidural technique for labor analgesia.
据我们所知,通过文献检索,这是首例关于病态肥胖(BMI = 66 kg/m²)的先兆子痫产妇成功进行剖宫产的病例报告,该产妇仅使用了极低剂量5毫克的高压脊麻布比卡因,未使用任何脊髓或静脉辅助用药。该产妇似乎对剖宫产脊髓麻醉的敏感性高于平均水平。对于此类病例,采用腰麻 - 硬膜外联合或硬膜外技术根据效果滴定神经轴药物而非单次脊麻可能是有用的。本报告并非建议常规使用无辅助用药的低剂量脊髓麻醉,而是说明了脊髓麻醉剂量和敏感性的广泛变异性,并表明该领域需要进一步研究,尤其是在病态肥胖产妇中。此外,它强调了即使在低剂量脊髓镇痛情况下,如用于分娩镇痛的腰麻 - 硬膜外联合技术,也要保持警惕并频繁监测血压和呼吸的重要性。