Baker Stuart G, Kramer Barnett S, Prorok Philip C
Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892-7354, USA.
Dis Markers. 2004;20(2):97-102. doi: 10.1155/2004/309391.
We provide a general framework for describing various roles for biomarkers in cancer prevention research (early detection, surrogate endpoint, and cohort identification for primary prevention) and the phases in their evaluation.
我们提供了一个通用框架,用于描述生物标志物在癌症预防研究中的各种作用(早期检测、替代终点以及一级预防的队列识别)及其评估阶段。