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不同体型患者腹股沟淋巴结的照射:技术比较及正常组织并发症发生概率

Irradiation of the inguinal lymph nodes in patients of differing body habitus: a comparison of techniques and resulting normal tissue complication probabilities.

作者信息

Brown Paul D, Kline Robert W, Petersen Ivy A, Haddock Michael G

机构信息

Division of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.

出版信息

Med Dosim. 2004 Fall;29(3):217-22. doi: 10.1016/j.meddos.2003.12.001.

Abstract

The treatment of the inguinal lymph nodes with radiotherapy is strongly influenced by the body habitus of the patient. The effect of 7 radiotherapy techniques on femoral head doses was studied. Three female patients of differing body habitus (ectomorph, mesomorph, endomorph) were selected. Radiation fields included the pelvis and contiguous inguinal regions and were representative of fields used in the treatment of cancers of the lower pelvis. Seven treatment techniques were compared. In the ectomorph and mesomorph, normal tissue complication probability (NTCP) for the femoral heads was lowest with use of anteroposterior (AP) and modified posteroanterior (PA) field with inguinal electron field supplements (technique 1). In the endomorph, NTCP was lowest with use of AP and modified PA field without electron field supplements (technique 2) or a 4-field approach (technique 6). Technique 1 for ectomorphs and mesomorphs and techniques 2 and 6 for endomorphs were optimal techniques for providing relatively homogeneous dose distributions within the target area while minimizing the dose to the femoral heads.

摘要

腹股沟淋巴结的放射治疗受到患者身体体型的强烈影响。研究了7种放射治疗技术对股骨头剂量的影响。选取了3名体型不同(瘦长型、匀称型、矮胖型)的女性患者。放射野包括骨盆及相邻的腹股沟区域,代表了用于治疗下骨盆癌症的放射野。比较了7种治疗技术。在瘦长型和匀称型患者中,使用前后位(AP)和改良后前位(PA)野加腹股沟电子野补充(技术1)时,股骨头的正常组织并发症概率(NTCP)最低。在矮胖型患者中,使用无电子野补充的AP和改良PA野(技术2)或四野照射法(技术6)时,NTCP最低。对于瘦长型和匀称型患者,技术1以及对于矮胖型患者,技术2和技术6是在靶区内提供相对均匀剂量分布同时使股骨头剂量最小化的最佳技术。

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