Thomas Nancy E, Groben Pamela
Department of Dermatology, University of North Carolina at Chapel Hill, NC 27599, USA.
J Am Acad Dermatol. 2004 Sep;51(3):466-70. doi: 10.1016/j.jaad.2004.04.027.
We provide documentation of the onset of 3 invasive superficial spreading melanomas arising from clinically normal skin and correlation with histologic lack of nevus association. Clinical, dermoscopic, and pathologic features of these "de novo" melanomas, which became invasive while small in diameter and had few clinical criteria for diagnosis, are reported.
我们提供了3例起源于临床正常皮肤的侵袭性浅表扩散性黑色素瘤发病情况的记录,并将其与组织学上缺乏痣相关性进行了关联分析。报告了这些“新发”黑色素瘤的临床、皮肤镜和病理特征,这些黑色素瘤在直径较小时就发生了侵袭,且几乎没有诊断的临床标准。