Roberts Kenny S, Sampson Nicole S
Department of Chemistry, State University of New York, Stony Brook, New York 11794-3400, USA.
Org Lett. 2004 Sep 16;6(19):3253-5. doi: 10.1021/ol048935y.
[structure: see text] To probe the activities of sperm ADAM protein (fertilinbeta), we devised a general synthetic strategy to generate fluorescently labeled fertilinbeta oligopeptide polymers. Immunofluorescence studies with these polymers demonstrated that fertilinbeta polymers bind specifically to a protein receptor on the mouse egg plasma membrane.
[结构：见正文] 为了探究精子ADAM蛋白（受精素β）的活性，我们设计了一种通用的合成策略来生成荧光标记的受精素β寡肽聚合物。用这些聚合物进行的免疫荧光研究表明，受精素β聚合物特异性结合到小鼠卵质膜上的一种蛋白质受体。
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