Fudala Paul J, Woody George W
Behavioral Health Service (116), Veterans Affairs Medical Center, Room B-228, University and Woodland Avenues, Philadelphia, PA 19104, USA.
Curr Psychiatry Rep. 2004 Oct;6(5):339-46. doi: 10.1007/s11920-004-0020-1.
Although addiction to heroin and other opiates is a major public health issue in the United States and many other countries, advances in pharmacologic and nonpharmacologic treatment have been made. Some of these advances represent a major shift from traditional treatment philosophies, whereas others are characterized by more subtle, though important, improvements. This review discusses recent advances in opiate-addiction treatment in the context of three main domains: the use of buprenorphine and buprenorphine/naloxone in an office-based paradigm, psychosocial treatment and the addressing of medical and psychiatric comorbidity, and harm reduction strategies.
尽管海洛因和其他阿片类药物成瘾在美国和许多其他国家都是一个重大的公共卫生问题，但在药物治疗和非药物治疗方面已经取得了进展。其中一些进展代表了与传统治疗理念的重大转变，而其他进展则以更细微但重要的改进为特征。本综述在三个主要领域的背景下讨论了阿片类药物成瘾治疗的最新进展：在门诊模式下使用丁丙诺啡和丁丙诺啡/纳洛酮、心理社会治疗以及对医疗和精神共病的处理，以及减少伤害策略。
