乳糜泻中的上皮内淋巴细胞：杀伤许可被揭示。
Intraepithelial lymphocytes in celiac disease: license to kill revealed.
作者信息
Sollid Ludvig M
机构信息
Institute of Immunology, Rikshospitalet, University of Oslo, N-0027, Norway.
出版信息
Immunity. 2004 Sep;21(3):303-4. doi: 10.1016/j.immuni.2004.08.002.
PMID:15357941
Abstract
Infiltration of lymphocytes in the small intestinal epithelium is a hallmark of active celiac disease. In this issue of Immunity, two papers uncover mechanisms controlling the cytolytic potential of these cells and provide evidence that lymphocyte killing of enterocytes is an important part of the celiac disease pathogenesis.
摘要
小肠上皮中淋巴细胞浸润是活动性乳糜泻的一个标志。在本期《免疫》杂志中，两篇论文揭示了控制这些细胞细胞溶解潜能的机制，并提供证据表明淋巴细胞对肠上皮细胞的杀伤是乳糜泻发病机制的重要组成部分。
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