Kim Dean Y, Stegall Mark D, Prieto Mikel, Chow George K, Bohorquez Humberto E, Covarrubias Marco A, Heimbach Julie K, Morgenstern Bruce Z, Gloor James M, Milliner Dawn S, Weckwerth Jody A, Weis Karla D, Ishitani Michael B
Department of Surgery, Division of Transplantation Surgery, William J. von Liebig Transplant Center, Mayo Medical School, Foundation and Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Pediatr Transplant. 2004 Oct;8(5):460-3. doi: 10.1111/j.1399-3046.2004.00195.x.
Laparoscopic donor nephrectomy (LDN) is the method of choice for procuring kidneys from living donors at many transplant centers. The aim of this study was to assess the feasibility as well as outcome of LDN in pediatric recipients. Twenty-two pediatric patients, 18-yr old or younger received kidneys procured by a hand-assisted LDN technique. The mean operative time was no different (p = 0.9) and the mean length of stay was more than 1 day shorter in the LDN group (p = 0.0001) compared with the 13 pediatric patients who received kidneys by standard open nephrectomy. Body mass index (BMI), number of donor kidney vessels, or laterality of the kidney did not impact the donor operation or outcome. Actuarial 1-yr patient survival was 100% and allograft survival was 95%, which are equivalent to registry data. There were no donor mortalities and there were five morbidities. None required hospitalization. There were no conversions from LDN to open nephrectomy. One kidney was lost because of overwhelming infection necessitating withdrawal of immunosuppression. In conclusion, hand-assisted LDN is a safe method of procuring kidneys from potential donors with no significant negative outcomes to the pediatric recipients.
腹腔镜供肾切除术(LDN)是许多移植中心从活体供体获取肾脏的首选方法。本研究的目的是评估LDN在儿科受者中的可行性及结果。22例18岁及以下的儿科患者接受了通过手辅助LDN技术获取的肾脏。与13例接受标准开放肾切除术获取肾脏的儿科患者相比,LDN组的平均手术时间无差异(p = 0.9),平均住院时间缩短超过1天(p = 0.0001)。体重指数(BMI)、供肾血管数量或肾脏的侧别均不影响供体手术或结果。1年实际患者生存率为100%,同种异体肾生存率为95%,与登记数据相当。没有供体死亡,有5例并发症。均无需住院治疗。没有从LDN转为开放肾切除术的情况。有1个肾脏因严重感染而丢失,需要停用免疫抑制治疗。总之,手辅助LDN是从潜在供体获取肾脏的一种安全方法,对儿科受者没有明显的负面结果。