Cox N H, Wilkinson D S
Department of Dermatology, Cumberland Infirmary, Carlisle, Cumbria, U.K.
Br J Dermatol. 1992 Jan;126(1):86-9. doi: 10.1111/j.1365-2133.1992.tb08411.x.
A female patient presented with two episodes of apparent dermatitis artefacta. Although it was clear that self-induced lesions were present on both occasions, there was also strong evidence in support of auto-erythrocyte sensitization syndrome on the first occasion and of naproxen-induced pseudoporphyria on the second occasion. The occurrence of two such rare disorders in a single patient is extremely unusual, and we discuss a possible pathogenetic link between them. The case emphasizes that patients with apparent artefactual lesions, or with a previous history of dermatitis artefacta, still require careful evaluation to identify organic disease.
一名女性患者出现了两次明显的人工性皮炎发作。尽管很明显两次发作时均存在自我诱导的损伤,但也有强有力的证据支持第一次发作时为自身红细胞致敏综合征,第二次发作时为萘普生诱发的假性卟啉症。单一患者出现两种如此罕见的疾病极为不寻常,我们讨论了它们之间可能的发病机制联系。该病例强调,有明显人工损伤的患者或有既往人工性皮炎病史的患者,仍需要仔细评估以识别器质性疾病。