Lenke Lawrence G, Newton Peter O, Marks Michelle C, Blanke Kathy M, Sides Brenda, Kim Yongjung J, Bridwell Keith H
Washington University School of Medicine, Department of Orthopaedic Surgery, St. Louis, MO 63110, USA.
Spine (Phila Pa 1976). 2004 Sep 15;29(18):2055-60. doi: 10.1097/01.brs.0000138274.09504.38.
Prospective clinical study.
To evaluate pulmonary function tests at a minimum 2-year follow-up in patients with adolescent idiopathic scoliosis (AIS) undergoing either an endoscopic versus open anterior fusion along with posterior segmental fixation and fusion.
A total of 21 patients with AIS underwent a video-assisted thoracoscopic (VAT group) release/fusion followed by a posterior spinal fusion (PSF) and segmental spinal fixation were compared to 16 patients who underwent an open thoracotomy (Open group) followed by a PSF. The mean preoperative thoracic Cobb was 70 degrees in the VAT group versus 75 degrees in the Open group. All patients had preoperative and a minimum 2-year postoperative pulmonary function tests consisting of forced vital capacity (FVC) forced expiratory volume in one second (FEV-1).
The average thoracic Cobb correction was to 27 degrees (61%) in the VAT group versus 36 degrees (52%) in the Open group. Preoperative and 2-year postoperative FVC in the VAT group averaged 2.48 L and 2.85 L, respectively (P = 0.006). The Open group corresponding results were 1.97 L and 2.43 L, respectively (P = 0.001). Preoperative and minimum 2-year postoperative FEV-1 in the VAT group averaged 2.06 L and 2.37 L, respectively (P = 0.005). Values for the Open group were 1.65 L and 2.08 L, respectively (P = 0.001). Although both groups had pulmonary function test parameters that were statistically improved postoperative versus preoperative, there were no significant differences comparing the VAT group to the Open group (P > 0.05)
VAT versus Open release/anterior fusion in association with a PSF for select AIS curves requiring circumferential treatment both demonstrated similar radiographic and pulmonary function test improvement at 2 years postoperative, with no significant differences seen between the groups.
前瞻性临床研究。
评估接受内镜下与开放性前路融合术联合后路节段性固定融合术治疗的青少年特发性脊柱侧凸(AIS)患者至少2年随访期的肺功能测试结果。
将21例行电视辅助胸腔镜手术(VAT组)松解/融合术并随后行后路脊柱融合术(PSF)及节段性脊柱固定术的AIS患者与16例行开放性开胸手术(开放组)并随后行PSF的患者进行比较。VAT组术前胸椎Cobb角平均为70度,开放组为75度。所有患者均进行了术前及术后至少2年的肺功能测试,包括用力肺活量(FVC)和一秒用力呼气量(FEV-1)。
VAT组胸椎Cobb角平均矫正至27度(61%),开放组为36度(52%)。VAT组术前及术后2年FVC平均分别为2.48L和2.85L(P = 0.006)。开放组相应结果分别为1.97L和2.43L(P = 0.001)。VAT组术前及术后至少2年FEV-1平均分别为2.06L和2.37L(P = 0.005)。开放组数值分别为1.65L和2.08L(P = 0.001)。尽管两组术后肺功能测试参数与术前相比均有统计学意义上的改善,但VAT组与开放组比较无显著差异(P>0.05)。
对于需要进行全周治疗的特定AIS曲线,VAT与开放性松解/前路融合联合PSF在术后2年均显示出相似的影像学和肺功能测试改善,两组间无显著差异。