Palou A, Bonet M L, Picó C, Rodríguez A M
Laboratori de Biologia Molecular, Nutrició i Biotecnologia, Universitat de les Illes Balears, Palma de Mallorca.
Rev Med Univ Navarra. 2004 Apr-Jun;48(2):36-48.
Obesity is a multifactorial disorder affected by multiple genetic and environmental factors, in particular nutrients, and their interrelationships. Increasing knowledge of the genes and molecules involved in the development of obesity is paving the way for new methods of obesity control. In this sense, Nutrigenomics--which represents a new approach in nutrition research that joints the application of powerful functional genomics technologies, bioinformatics and molecular biology with more traditional methodologies--may orientate the design and development of new functional foods for obesity, based on the scientific knowledge of the impact of specific nutrients on the mammalian body weight control system and their mechanisms of action.
肥胖是一种受多种遗传和环境因素影响的多因素疾病,尤其是营养物质及其相互关系。对肥胖发生过程中涉及的基因和分子的认识不断增加,为肥胖控制的新方法铺平了道路。从这个意义上说,营养基因组学——它代表了营养研究中的一种新方法,将强大的功能基因组学技术、生物信息学和分子生物学与更传统的方法结合起来——可以基于特定营养物质对哺乳动物体重控制系统及其作用机制影响的科学知识,为肥胖症新功能食品的设计和开发提供指导。