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自体骨软骨移植治疗肩关节全层关节软骨缺损

Osteochondral autologous transplantation for the treatment of full-thickness articular cartilage defects of the shoulder.

作者信息

Scheibel M, Bartl C, Magosch P, Lichtenberg S, Habermeyer P

机构信息

Department of Shoulder and Elbow Surgery, ATOS-Clinic Heidelberg, Bismarckplatz 915, 69115 Heidelberg, Germany.

出版信息

J Bone Joint Surg Br. 2004 Sep;86(7):991-7. doi: 10.1302/0301-620x.86b7.14941.

Abstract

We performed eight osteochondral autologous transplantations from the knee joint to the shoulder. All patients (six men, two women; mean age 43.1 years) were documented prospectively. In each patient the stage of the osteochondral lesion was Outerbridge grade IV with a mean size of the affected area of 150 mm2. All patients were assessed by using the Constant score for the shoulder and the Lysholm score for the knee. Standard radiographs, magnetic resonance imaging and second-look arthroscopy were used to assess the presence of glenohumeral osteoarthritis and the integrity of the grafts. After a mean of 32.6 months (8 to 47), the mean Constant score increased significantly. Magnetic resonance imaging revealed good osseointegration of the osteochondral plugs and congruent articular cartilage at the transplantation site in all but one patient. Second-look arthroscopy performed in two cases revealed a macroscopically good integration of the autograft with an intact articular surface. Osteochondral autologous transplantation in the shoulder appears to offer good clinical results for treating full-thickness osteochondral lesions of the glenohumeral joint. However, our study suggests that the development of osteoarthritis and the progression of pre-existing osteoarthritic changes cannot be altered by this technique.

摘要

我们对8例患者进行了从膝关节到肩关节的自体骨软骨移植。所有患者(6名男性,2名女性;平均年龄43.1岁)均进行了前瞻性记录。每位患者的骨软骨损伤均为Outerbridge IV级,平均受累面积为150平方毫米。所有患者均采用肩关节Constant评分和膝关节Lysholm评分进行评估。使用标准X线片、磁共振成像和二次关节镜检查来评估盂肱关节炎的存在情况以及移植物的完整性。平均32.6个月(8至47个月)后,Constant评分显著提高。磁共振成像显示,除1例患者外,所有患者的骨软骨栓均实现了良好的骨整合,移植部位的关节软骨也保持一致。2例患者接受的二次关节镜检查显示,自体移植物在宏观上实现了良好的整合,关节表面完整。自体骨软骨移植术治疗盂肱关节全层骨软骨损伤似乎能取得良好的临床效果。然而,我们的研究表明,该技术无法改变骨关节炎的发展以及既往存在的骨关节炎病变的进展。

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