Nishikawa Masanori, Tsuzaki Yoshihiko, Maoka Kazuya, Nishida Takehito, Sakamoto Kozo, Yamamoto Gaku
Dept. of Oral and Maxillofacial Surgery, Shiga University of Medical Science.
Gan To Kagaku Ryoho. 2004 Sep;31(9):1383-5.
We report a patient showing a complete remission after combination chemotherapy with nedaplatin and 5-fluorouracil (5-FU). A 63-year-old man was admitted to our hospital for advanced carcinoma of gingiva. 5-FU was administered at a dose of 1,000 mg/body (700 mg/m2) by continuous infusion for 120 hours on days 1 to 5. Nedaplatin was administered at a dose of 140 mg/body (90 mg/m2) by drip infusion for 120 minutes on day 5. This combination chemotherapy resulted in a complete remission of the tumor after 2 weeks. There has been no sign of recurrence for 6 months after the chemotherapy.