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使用左心室-肺动脉导管对房室连接不一致且伴有肺动脉流出道梗阻的患者进行双心室功能修复——导管梗阻会维持三尖瓣功能吗?

Functional biventricular repair using left ventricle-pulmonary artery conduit in patients with discordant atrioventricular connections and pulmonary outflow tract obstruction-does conduit obstruction maintain tricuspid valve function?

作者信息

Koh Masahiro, Yagihara Toshikatsu, Uemura Hideki, Kagisaki Koji, Kitamura Soichiro

机构信息

Department of Cardiovascular Surgery, National Cardiovascular Center, 5-7-1 Fujishiro-dai, 565-8565 Suita, Osaka, Japan.

出版信息

Eur J Cardiothorac Surg. 2004 Oct;26(4):767-72. doi: 10.1016/j.ejcts.2004.05.051.

Abstract

OBJECTIVE

The aim of the study is to determine whether function of the tricuspid valve placed for the systemic circulation is related to left ventricular pressure supporting the pulmonary circulation after functional repair for atrioventricular discordance.

METHODS

Right ventricular volume and tricuspid regurgitation (TR) were investigated, in relation to left ventricular pressure, in 15 patients with this malformation who underwent functional biventricular repair with left ventricle-pulmonary artery conduit.

RESULTS

After the functional biventricular repair, ratio of systolic left ventricular pressure to right ventricular one (LVP/RVP) was 0.58+/-0.24 and right ventricular end-diastolic pressure (RVEDV) significantly increased from 104+/-24 to 137+/-39% of normal predicted value (P = 0.015). Five patients with LVP/RVP>0.6 were free from TR, however, six of seven with LVP/RVP<0.6 developed TR. Three patients required eventual tricupid valve replacement. Conduit replacement was required in seven patients and five were assessed similarly. After the conduit replacement, LVP/RVP decreased from 1.08+/-0.34 to 0.58+/-0.14 and RVEDV increased significantly from 87+/-24 to 129+/-19% (P = 0.011). One patient with postoperative LVP/RVP of 0.36 developed moderate TR.

CONCLUSION

Mild obstruction at the pulmonary channel is not necessarily an evil after functional biventricular repair for this malformation, in terms of TR and right ventricular dilatation.

摘要

目的

本研究旨在确定在房室不一致功能性修复后,用于体循环的三尖瓣功能是否与支持肺循环的左心室压力相关。

方法

对15例患有这种畸形并接受左心室-肺动脉导管功能性双心室修复的患者,研究右心室容积和三尖瓣反流(TR)与左心室压力的关系。

结果

功能性双心室修复后,左心室收缩压与右心室收缩压之比(LVP/RVP)为0.58±0.24,右心室舒张末期压力(RVEDV)从正常预测值的104±24%显著增加至137±39%(P = 0.015)。5例LVP/RVP>0.6的患者无TR,然而,7例LVP/RVP<0.6的患者中有6例出现TR。3例患者最终需要更换三尖瓣。7例患者需要更换导管,对其中5例进行了类似评估。更换导管后,LVP/RVP从1.08±0.34降至0.58±0.14,RVEDV从87±24%显著增加至129±19%(P = 0.011)。1例术后LVP/RVP为0.36的患者出现中度TR。

结论

就TR和右心室扩张而言,对于这种畸形进行功能性双心室修复后,肺通道轻度梗阻不一定是坏事。

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