Jones L, Lott M F, Calder C J, Kutt E
Avon Breast Screening Centre, Central Clinic, Tower Hill, Bristol, UK.
Clin Radiol. 2004 Oct;59(10):903-8. doi: 10.1016/j.crad.2004.02.016.
To investigate whether imprint cytology from ultrasound-guided core biopsy specimens was adequate for the National Health Service Breast Screening Programme (NHSBSP) guidelines.
We prospectively audited imprint cytology from ultrasound-guided core biopsy specimens. The performance indicators for imprint cytology specimens from 111 consecutive ultrasound-guided core biopsy were compared with standards set by the NHSBSP for fine-needle aspiration cytology (FNAC).
Imprint cytology fulfilled the "preferred" targets for absolute and complete sensitivity, specificity, positive predictive value, false-positive and false-negative rates, inadequate rate and inadequate rate from cancers. It also satisfied the minimum target for suspicious rate. The complete sensitivity was 97%, full specificity 78%, with 100% positive predictive value for C5 cytology and an inadequate rate from cancers of 1.5%.
Imprint cytology from ultrasound-guided core biopsy allows same-day diagnosis and the collection of data regarding the grade of the carcinoma for treatment decisions from a single needle test.
调查超声引导下粗针穿刺活检标本的印片细胞学检查是否符合英国国家医疗服务体系乳腺筛查计划（NHSBSP）的指南。
我们对超声引导下粗针穿刺活检标本的印片细胞学检查进行了前瞻性审核。将111例连续超声引导下粗针穿刺活检的印片细胞学标本的性能指标与NHSBSP设定的细针穿刺抽吸细胞学检查（FNAC）标准进行比较。
印片细胞学检查在绝对和完全敏感性、特异性、阳性预测值、假阳性和假阴性率、不充分率以及癌症不充分率方面达到了“首选”目标。它也满足了可疑率的最低目标。完全敏感性为97%，完全特异性为78%，C5细胞学的阳性预测值为100%，癌症的不充分率为1.5%。
超声引导下粗针穿刺活检的印片细胞学检查可实现当日诊断，并能通过单次针吸检查收集有关癌分级的数据，以用于治疗决策。
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